WebJun 15, 1998 · PTT consists of the unusual amino acid phosphinothricin (PT) and two alanine residues, which are linked non-ribosomally by peptide synthetases. The structurally identical compound bialaphos is produced by Streptomyces hygroscopicus [2]. WebJul 1, 2009 · One such compound, phosphinothricin tripeptide, contains the unusual amino acid phosphinothricin attached to two alanine residues. Synthetic phosphinothricin (glufosinate) is a component of two ...
Isolation and characterization of the PEP-phosphomutase and the ...
WebThe biosynthesis of PTT includes the synthesis of the unusual amino acid N-acetyl-demethyl-phosphinothricin and a three step condensation via non-ribosomal peptide … WebSubsequent tissue culture and regeneration steps allow recovery of plantlets, assisted by the inclusion of PPT (phosphinothricin tripeptide), the active ingredient of glufosinate-ammonium containing herbicides, to help select transformants. This updated method introduces selection earlier in the regeneration process which provides a shortened ... small claims court botswana
Phosphinothricin - an overview ScienceDirect Topics
WebMolecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736. JAV Blodgett, JK Zhang, WW Metcalf. ASM Antimicrobial Agents and Chemotherapy, 2005. PMID: 15616300; PMC: PMC538901; DOI: 10.1128/AAC.49.1.230-240.2005 in the news: … In the 1960s and early 1970s, scientists at University of Tübingen and at the Meiji Seika Kaisha Company independently discovered that species of Streptomyces bacteria produce a tripeptide they called bialaphos that inhibits bacteria; it consists of two alanine residues and a unique amino acid that is an analog of glutamate that they named "phosphinothricin". They determined that phosphinothricin irreversibly inhibits glutamine synthetase. Phosphinothricin was first synthesize… WebSummary: L-phosphinothricin is a non-proteinogenic amino acid that is a structural analogue of L-glutamate.As such, it is a potent inhibitor of glutamine synthetase, an enzyme central to nitrogen regulation in many bacterial and plant species [Bayer72, Lea84].It is the active ingredient in several nonselective systemic herbicides, including Basta, Rely, Finale, … small claims court belfast contact number