Cisplatin and radiotherapy

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August undefined, 2024

WebThe number of cisplatin-induced DNA adducts and radiation-induced strand breaks after a given dose of each agent are known for given cell systems, from which the probability that these lesions will interact can be estimated. WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in …

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WebMay 1, 2005 · Abstract. The combination of cisplatin and ionizing radiation (IR) treatment represents a common modality for treating a variety of cancers. These two agents provide considerable synergy during treatment, although the mechanism of this synergy remains largely undefined. We have investigated the mechanism of cisplatin sensitization to IR … WebPurpose: Although commonly used for the treatment of locally advanced head and neck squamous cell carcinoma (HNSCC) concomitant radio-chemotherapy (RT-CT) with … c-type lectin domain

Cisplatin and radiotherapy in the treatment of locally ... - PubMed

http://www.nrgoncology.org/Home/News/Post/adding-atezolizumab-to-cisplatin-and-radiotherapy-for-node-positive-locally-advanced-cervical-cancer-nrg-gy017 WebOct 14, 2024 · We performed an open-label randomized controlled phase III study comparing treatment outcome and toxicity between radiotherapy (RT) with concomitant cisplatin versus concomitant cetuximab in … WebApr 13, 2024 · HIGHLIGHTS who: Florentine S. B. Subtil et al. from the Department of Radiotherapy and Radiooncology, Philipps-University, Marburg, Germany have published the research: Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic … Dual pi3k/mtor inhibitor nvp-bez235 leads to a synergistic enhancement of cisplatin and … easing after effects

Cetuximab and Radiation Therapy Versus Cisplatin and Radiation …

[Cisplatin and radiotherapy] - PubMed

WebConcurrent cisplatin-based chemoradiotherapy versus exclusive radiotherapy in high-risk cervical cancer: a meta-analysis Xiang-Yu Meng,1,* Yi Liao,2,* Xiao-Ping Liu,3 Sheng … WebRadiotherapy treats cancer by using high-energy x-rays. These destroy the cancer cells while doing as little harm as possible to normal cells. You may have radiotherapy: if you have early or locally advanced cervical cancer. after surgery, if there is a high risk of the cancer coming back. if cancer comes back in the pelvis after surgery. c-type lectin receptor 信号通路WebOf the numerous clinical trials published on such combined chemo-radiotherapy, 16 were selected for analysis fulfilling the following criteria: cisplatin used as the sole chemotherapeutic agent in combination with radiation for patients with unresectable squamous cell carcinomas of the head and neck, with no previous treatment for the … easing alcohol withdrawal symptoms

"WebApr 5, 2024 · A review of literature was conducted in Pubmed, Scopus, and Medline to compare and evaluate the present role of weekly cisplatin chemotherapy along with radiotherapy versus 3-weekly cisplatin chemotherapy along with radiotherapy in both adjuvant and definitive settings for locoregionally advanced head and neck cancers. " - Cisplatin and radiotherapy

Cisplatin and radiotherapy

Cisplatin Sensitizes Cancer Cells to Ionizing Radiation via …

WebSep 3, 1991 · After a preliminary dose-finding study involving 12 patients with advanced or locally recurrent head and neck cancer, 27 patients were treated on a phase II protocol, … WebEffect of the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation Therapy for Patients With Esophageal Cancer: The NRG Oncology RTOG 0436 Phase 3 Randomized Clinical Trial Esophageal Cancer JAMA Oncology JAMA Network

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WebHow Cisplatin + radiation chemotherapy is given and possible side effects. Cisplatin + radiation for the treatment of Head and Neck Cancer Cisplatin + Radiation is used in the treatment of head and neck cancer. MOST COMMON SIDE EFFECTS OF CISPLATIN + RADIATION Infection Mouth Sores Nausea & Vomiting Neuropathy WebCisplatin is approved to be used alone or with other drugs to treat: Bladder cancer. It is used alone in patients with advanced cancer that cannot be treated with other therapies, such as surgery or radiation therapy. Ovarian cancer that …

WebMar 20, 2014 · Cisplatin and Irinotecan (Camptosar) Paclitaxel (Taxol) and either 5-FU or capecitabine Other common drugs and drug combinations that can be used to treat esophageal cancer but are usually not given with radiation include: ECF: epirubicin (Ellence), cisplatin, and 5-FU (especially for gastroesophageal junction tumors) WebFeb 11, 2024 · Background Concurrent chemoradiotherapy with cisplatin is standard for patients (pts) with loco-regionally advanced squamous cell carcinoma of the head and …

WebJun 4, 2024 · Weekly cisplatin plus radiotherapy (RT) should be considered standard care in patients with locally advanced head and neck squamous cell carcinoma (HNSCC), according to researchers. WebConcurrent cisplatin and radiation therapy is a potentially curative and conservative treatment for patients with localized muscle invasive bladder cancer who are not …

WebNov 15, 2010 · (†) Carboplatin area under the curve (AUC) 1.5 substitution for intolerable cisplatin-related toxicities during definitive therapy with radiotherapy, cisplatin, and cetuximab (XPE) only. (‡) With prophylactic antibiotics (ie, ciprofloxacin on days 5 to 14 of each induction therapy with docetaxel, cisplatin, and cetuximab [TPE] cycle).

WebFeb 1, 2024 · Fluorouracil + Cisplatin + Radiotherapy 5,7,b,c. Days 1-4, 29-32: Fluorouracil 1,000mg/m 2 IV continuous infusion over 24 hours. Days 1,29: Cisplatin 75mg/m 2 IV over 2 hours. easing anemia symptomsWebCisplatin–etoposide combined with once-daily radiotherapy was also examined in pilot studies. 8,9 The Southwest Oncology Group, using daily fractionated thoracic radiotherapy at a total dose... c−type lectin receptor signaling pathway翻译WebApr 12, 2024 · The patient was started on gemcitabine, cisplatin, and nanoparticle albumin-bound paclitaxel (nab-paclitaxel). After 3 months of chemotherapy, the patient's AFP increased to 43.8 ng/ml and her CA 19-9 increased to 21.4 U/ml. ... Data from one meta-analysis demonstrated a benefit in OS related to adjuvant radiation therapy among … c-type lectin-like receptorsWebCisplatin-based concurrent chemoradiotherapy (CCRT) has become a standard treatment for cancer of the uterine cervix. However, there have been no investigations into the optimum timing for administration of anticancer drugs using animal models. easing aqua solutionsWebJan 28, 2024 · Cisplatin may enact subtle long-term effects. 36,37 In a laryngeal cancer phase III clinical trial more noncancer-related deaths were observed at long-term follow-up in patients receiving concurrent CRT as compared with those treated with induction chemotherapy followed by radiation or radiation alone. 38 However, in the HPV … c-type lectin receptor信号通路WebNov 1, 2004 · Purpose: To evaluate patient compliance and acute toxicity accompanying concurrent weekly cisplatin and radiotherapy (RT) in the routine management of cervical cancer. Methods and materials: Locally advanced or high-risk early-stage cervical cancer patients treated with RT and concurrent weekly cisplatin at a dose of 40 mg/m(2) i.v. … easing anxiety d e fosterWebConcurrent cisplatin-based chemoradiotherapy versus exclusive radiotherapy in high-risk cervical cancer: a meta-analysis Xiang-Yu Meng,1,* Yi Liao,2,* Xiao-Ping Liu,3 Sheng Li,1 Ming-Jun Shi,4 Xian-Tao Zeng11Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, People’s Republic of … easing a chesty cough